BIONIC: Biological Stent Anchoring for Fewer Complications in Cardiovascular Aneurysms

Optimized Cardiovascular Stents

This SNN-JTF project focuses on the development of advanced endovascular stents for the treatment of aneurysms. Aneurysms are dangerous dilations in blood vessels that can be life-threatening if they rupture. Endovascular stents are used to reinforce the vessel wall, but are often associated with complications such as fibrosis, infections, immune reactions, leaks, blockages, displacement, or fractures.

To prevent these complications, BiomACS’s screening technology will conduct large-scale testing of combinations of surface properties—such as hydrophobicity, stiffness, and topography—to assess their impact on cell behavior. The goal is then to develop an endovascular stent with an optimized surface that actively stimulates adhesion to the vessel wall. This will reduce complications and increase patient safety.

This project is made possible by the following organizations: